Cross-Sectional Study - Diversity Outbred (J:DO)

Project Aims:

Characterization of healthspan and lifespan in J:DO mice investigating early, mid-life and late life biomarkers of aging. Establishment of a tissue bank to provide aged J:DO resources to the scientific community.


Project Start/End Dates: July 2011 – March 2014
Strain(s): J:DO (Stock 009376)
Quantity/Sex/Age of Animals:

300 females and 300 males

6, 12, and 18 month timepoints

Diet: 5K52 6%
Phenotyping Assays: Open Field, Novel Object, T-maze, Light/Dark,Tail Suspension, Urinary Incontinence, Urine Analysis, Fecal Analysis, PIXI, Grip and Rotarod.
Animal Resources:

Fat Pad, Muscle, Heart, Liver, Kidney

Link to Open Resources